Soyal Khan

New Research Shows Neurogenesis, Birth Of New Brain Cells, Continues In The Hippocampus Into Old Age, Though Formation Rates Decline With Age And Vary Individually. Using RNA Sequencing & Machine Learning On Postmortem Brains Aged 0–78, Scientists Found Immature Neurons. These Findings Could Aid Neurodegenerative & Psychiatric Treatments.

…

US Scientists Found That The Protein Ferritin Light Chain 1 (FTL1) May Drive Brain Aging By Reducing Cognition & Hippocampus Brain Cell (HBC) Connections. Increasing FTL1 In Young Mice Prematurely Aged Their Brains, While Lowering It In Old Mice Reversed Decline. Boosting HBC Metabolism Also Helped. Study Offers Hope To Reverse Brain Aging.

…

UQ Scientists Created The World’s First Lab-Grown Human Skin Organoids From Stem Cells, Complete With Blood Vessels, Hair Follicles, & Immune Cells. Developed Over 6 Yrs, This Life-Like Skin Enables Breakthroughs In Treating Burns, Graft Transplants, Wound Healing, Chronic Disorders Like Psoriasis & Scleroderma, And Research & Drug Testing.

Jan Janisch-Hanzlik, Nebraska, Became The World’s First Multiple Sclerosis Patient To Receive Donor-Derived (DD) CAR T-Cell Therapy. After Standard Treatments Failed, She Joined A Phase-1 Trial Using DD T-Cells To Target Immune Cells Driving MS. Within 60 Days, Her Dramatic Progress Sparked Hope For Future MS Care & Potential Phase-2 Expansion.

Comet 3I/ATLAS, Spotted By ATLAS In Chile, Is The Fastest Comet Ever At 130k Mph. Likely From A Distant Solar System, Its Speed Comes From Billions Of Years Of Gravitational Slingshots. Hubble Showed Its 1k Ft To 3.5-Mile-Wide Icy Core & Dust Tail. Nearing The Sun By 10/25, It May Disintegrate Or Survive/Speed Up; Its Fate Will Be Clear By 12/25.

Researchers Found That Injecting Reduced HMGB1 Protein From An Oxygen-Free Env. Can Trigger Aging In Healthy Human And Mice Cells, Causing Them To Stop Dividing & Deteriorate. Older Adults’ Blood Has More Of This Reduced HMGB1, Suggesting Aging May Spread Via Blood Signals & Not Just Within Cells, Opening Doors For Anti-Aging Therapies.

…

Astronomers Found A Dormant Black Hole (BH) In Galaxy SDSS J1148+1930, 5B Ly Away, Weighing 36.3B Solar Masses (SM), Likely The Largest Confirmed Due To Precise Measurement Via Gravitational Lensing & Stellar Kinematics. Likely Formed From BH Mergers, It Nears The 50B BH SM Theoretical Cap. TON 618’s SM Was Revised To ~40B With Uncertainty.

…

In A World First, A Man With Type 1 Diabetes Produced His Own Insulin After Receiving CRISPR-Edited Insulin-Making Pancreatic Islet Cells. CRISPR Reduced Immune-Triggering Proteins & Boosted CD47 To Avoid Rejection Without Immunosuppressants. Injected Into His Forearm, The Cells Still Function 12 Weeks Later, Marking A Potential Cure Step.

…

Harvard Researchers, In A World First, Found That Low Brain Lithium May Trigger Alzheimer’s. In Mice & Hundreds Of Human Samples, Levels Fell As Disease Progressed, Worsening Inflammation, Memory Loss, Amyloid Beta Plaques, And Tau Tangles. Lithium Orotate Reversed Damage In Mice, But No Clinical Trials Confirm Effects In Living Patients.

…

Astronomers Found The Oldest, Most Distant Black Hole (BH), Formed ~13.3B Yrs Ago In Galaxy (G) CAPERS-LRD-z9. The BH Is ~300M× Our Sun’s Mass & ~10× Milky Way’s BH. The G, In The “Little Red Dots” Class, Is Compact, Bright, And Red; With Red Color Cause Unclear. Both BH & G, Found Via JWST Spectroscopy, Offer Clues To Early G/BH Evolution.

…