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In A First, Researchers Found A Denisovan (DN) Gene, MUC19, In Humans Passed On Via Neanderthal (ND) DNA. DNs Interbred With NDs; Then NDs Later Interbred With Early Modern Humans, Passing The Gene To Early Americans. This Gene Transfer, Found In 1 In 3 Mexicans Today, May Have Helped Against Diseases As Humans Migrated Across The Americas.

The first Americans had Denisovan DNA. And it may have helped them survive. | Live Science

https://www.livescience.com/archaeology/human-evolution/the-first-americans-had-denisovan-dna-and-it-may-have-helped-them-survive

People with Indigenous American ancestry carry Denisovan genes that Neanderthals passed on when they mated with modern humans.