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A Recent And Previous Studies Seem To Indicate That Abnormally Folded Alpha-synuclein, A Natural Protein And A Key Player For Parkinson’s Disease, May Start Off In The Gut Before Extending To The Brain. This Discovery May Help Scientists Combat Parkinson’s Disease At A Very Pre-Early Stage.

https://www.theguardian.com/society/2019/jun/26/growing-evidence-suggests-parkinsons-disease-starts-in-gut

Research shows key proteins in disease can spread from gastrointestinal tract to brain